Flavonoid as Anti-Candida Agents

Vulvovaginal candidiasis is the second most common cause of vaginitis after bacterial vaginosis with at least 75 – 80% women have had one episode VVC in their lifetime. Their prevalent resistance to commonly used antifungal agents makes treatment a challenge physicians. Flavonoids been shown possess potent anti-Candida properties which can inhibit growth and proliferation Candida species through various mechanisms, including inhibition fungal cell wall synthesis, disruption membrane integrity, interference signaling pathways. potency them potential candidates for development candidiasis, alone or combination existing drugs. The review aims explore mechanisms by flavonoids species,